Tofacitinib citrate

A potet JAK inhibitor

Cat. No.: AUR11052

CAS Number: 540737-29-9

Documents:

SizePrice

100 mg

$ 175

Tags Tofacitinib tofacitinib citrate CP-690550 CP690550 JAK1 inhibitor JAK inhibitor CAS#540737-29-9 540737-29-9 Auroramedbiochem

Alternate Names

3-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile citrate; CP-690550

Appearance

White to off-white solid

Formulation

n/a

CAS Number

540737-29-9

Molecular Formula

C16H20N6O.C6H8O7

Molecular Weight

504.49

Purity

≥98% by HPLC

Solubility

DMSO (~5 mg/ml)

Handling

Protect from air and light

Country of origin

USA

Storage temperature

-20°C

Shipping Condition

gel pack

Shelf life

24 months

MDL number

MFCD11616529

PubChem CID

10174505

SMILES

CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

InChI

InChI=1S/C16H20N6O.C6H8O7/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16;7-3(8)1-6(13,5(11)12)2-4(9)10/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/t11-,13+;/m1./s1

InChI key

SYIKUFDOYJFGBQ-YLAFAASESA-N

Tofacitinib citrate is an orally available JAK1/2/3 inhibitor with IC50s of 1, 20, and 112 nM, respectively. Tofacitinib citrate has antibacterial, antifungal and antiviral activities.

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