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ABT-888

Cat. No.: AUR10032

CAS Number: 912445-05-7

Potent inhibitor of PARP-1 and PARP-2 (potency ≤5 nM in vitro).

Actinomycin D

Cat. No.: AUR10033

CAS Number: 50-76-0

An antineoplastic antibiotic. Inhibits DNA-primed RNA polymerase by complexing with DNA via deoxyguanosine residues.

SolutionReady™ Actinomycin D

Cat. No.: AUR10034

CAS Number: 50-76-0

A solution (2 mg/ml) of the antineoplastic antibiotic in anhydrous DMSO.

AEBSF.HCl

Cat. No.: AUR10030

CAS Number: 30827-99-7

A specific, irreversible serine protease inhibitor. Inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin and trypsin. A stable, non-toxic and better soluble alternative to PMSF.

AG-1295

Cat. No.: AUR11147

CAS Number: 71897-07-9

AG-1295 is a selective platelet-derived growth factor receptor (PDGFR) tyrosine-kinase inhibitor.

Akt Activator II, SC79

Cat. No.: AUR10056

CAS Number: 305834-79-1

SC79 is a specific and BBB permeable Akt activator that activates Akt in the cytosol and inhibits Akt membrane translocation.

Akt Inhibitor XIV

Cat. No.: AUR10072

CAS Number: 1191951-57-1

A potent thiadiazolyl analog that binds to PH (pleckstrin homology) domain (Kd = 40.8 µM, Ki = 2.4 µM)..

Argonaute-2 Inhibitor, BCI-137

Cat. No.: AUR10089

CAS Number: 112170-24-8

A cell-permeable compound that directly and reversibly interacts with miRNA binding domain of Argonaute-2 (Kd = 126 µM) and inhibits binding of miR-20a, miR-26a, miR-107, miR-223 & let-7a to Ago2.

AS-1842856

Cat. No.: AUR10392

CAS Number: 836620-48-5

AS 1842856 is a potent and selective Foxo1 inhibitor (IC50 values are 33 nM at Foxo1 and >1 μM at Foxo3a and Foxo4)

ASB-14

Cat. No.: AUR10110

CAS Number: 216667-08-2

A zwitterionic detergent useful for the solubilization of proteins including previously undetected membrane proteins. ASB-14 exhibits better protein solubilization properties than CHAPS. Also useful for solubilizing proteins for 2D-gel electrophoresis.

ASB-16

Cat. No.: AUR10112

CAS Number: 52562-29-5

ASB-16 is a useful zwitterionic detergent for the solubilization of proteins including previously undetected membrane proteins. ASB-16 exhibits better protein solubilization properties than CHAPS. Also useful for solubilizing proteins for 2D-gel electrophoresis.

Atglistatin

Cat. No.: AUR10107

CAS Number: 1469924-27-3

Atglistatin is a potent, selective, and competitive inhibitor of ATGL (IC50 = 0.7 μM). It does not inhibit hormone-sensitive lipase, monoglyceride lipase, pancreatic lipase, lipoprotein lipase, or other lysophospholipases.

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