JAK3 Inhibitor II, WHI-P154

A potent JAK3 inhibitor

Cat. No.: AUR10520

CAS Number: 211555-04-3

Documents:

SizePrice

100 mg

$ 1225

Tags WHI-P154 WHIP154 JAK3 Inhibitor CAS#211555-04-3 211555-04-3 Auroramedbiochem

Alternate Names

2-bromo-4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol; WHI-P154

Appearance

Pale yellow solid

Formulation

N/A

CAS Number

211555-04-3

Molecular Formula

C16H14BrN3O3

Molecular Weight

376.2

Purity

>97% by HPLC

Solubility

DMSO (100 mg/ml)

Handling

Protect from air and light

Country of origin

USA

Storage temperature

-20°C

Shipping Condition

Shelf life

24 months

MDL number

MFCD02179366

PubChem CID

3795

SMILES

COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)O)Br)OC

InChI

InChI=1S/C16H14BrN3O3/c1-22-14-6-10-12(7-15(14)23-2)18-8-19-16(10)20-9-3-4-13(21)11(17)5-9/h3-8,21H,1-2H3,(H,18,19,20)

InChI key

CBIAKDAYHRWZCU-UHFFFAOYSA-N

WHI-P154 is a potent, cell-permeable, reversible, ATP-competitive, and specific inhibitor of JAK3 (IC50 = 5.6 µM). Has no effect on either JAK1 or JAK2.

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