AG-1295 is a selective platelet-derived growth factor receptor (PDGFR) tyrosine-kinase inhibitor.
SC79 is a specific and BBB permeable Akt activator that activates Akt in the cytosol and inhibits Akt membrane translocation.
A potent thiadiazolyl analog that binds to PH (pleckstrin homology) domain (Kd = 40.8 µM, Ki = 2.4 µM)..
A cell-permeable compound that directly and reversibly interacts with miRNA binding domain of Argonaute-2 (Kd = 126 µM) and inhibits binding of miR-20a, miR-26a, miR-107, miR-223 & let-7a to Ago2.
AS 1842856 is a potent and selective Foxo1 inhibitor (IC50 values are 33 nM at Foxo1 and >1 μM at Foxo3a and Foxo4)
ASB-16 is a useful zwitterionic detergent for the solubilization of proteins including previously undetected membrane proteins. ASB-16 exhibits better protein solubilization properties than CHAPS. Also useful for solubilizing proteins for 2D-gel electrophoresis.
Atglistatin is a potent, selective, and competitive inhibitor of ATGL (IC50 = 0.7 μM). It does not inhibit hormone-sensitive lipase, monoglyceride lipase, pancreatic lipase, lipoprotein lipase, or other lysophospholipases.
BAPTA, Tetrasodium Salt is a selective calcium chelator with 105-fold greater affinity for Ca2+ than for Mg2+. This product is a high quality and sensitive compound for calcium signaling studies, investigation of signal transduction and apoptotic cascades, and neuroscience research.
BAPTA/AM is a cell-permeable form of BAPTA (Cat. No. AUR1014). Can be loaded into a wide variety of cells, where it is hydrolyzed by cytosolic esterases and is trapped intracellularly as the active chelator BAPTA.
Bestatin is a protease Inhibitor that reversibly inhibits amino peptidases.
BLT-1 is a novel inhibitor of scavenger receptor BI (SR-BI).
A01 is a high affinity Smurf1 E3 ubiquitin ligase inhibitor (Kd = 3.7 nM). Attenuates Smurf1-mediated Smad 1/5 degradation and enhances BMP signaling. Potentiates BMP-2-induced osteoblastic activity in C2C12 myoblasts and MC3T3-E1 osteoblast precursor cells.
