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SB 203580

SB 203580

A potent MAP kinase inhibitor

Cat. No.: AUR10910

CAS Number: 152121-47-6

Documents:              

SizePrice

$ 395 
  
Tags SB203580 152121-47-6 152121476 MAP kinase inhibitor CAS#152121-47-6 Auroramedbiochem

Alternate Names

[4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole

Appearance

White to off-white solid

Formulation

N/A

CAS Number

152121-47-6

Molecular Formula

C₂₁H₁₆FN₃OS

Molecular Weight

377.43

Purity

≥98% by HPLC

Solubility

DMSO (>20 mg/ml) or warm ethanol (12 mg/ml)

Handling

Protect from air and light

Country of origin

USA

Storage temperature

-20°C

Shipping Condition

RT

Shelf life

24 months

MDL number

MFCD00922198

PubChem CID

176155

SMILES

CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F

InChI

InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)

InChI key

CDMGBJANTYXAIV-UHFFFAOYSA-N

Cell-permeable. Selective inhibitor of p38 mitogen-activated protein kinase (MAP Kinase) (IC₅₀ values are 50 and 500 nM for SAPK2a/p38 and SAPK2b/p38β2 respectively). Displays 100-500-fold selectivity over LCK, GSK3β and PKBα.

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