STAT3 Inhibitor XVIII, BP-1-102

A potent and selective STAT3 inhibitor

Cat. No.: AUR11018

CAS Number: 1334493-07-0

Documents:

SizePrice

100 mg

$ 1150

Tags BP-1-102 stat3 inhibitor BP1-102 Stat3-phospho-tyrosine CAS# 1334493-07-0 1334493-07-0 Auroramedbiochem

Alternate Names

Appearance

White solid

Formulation

N/A

CAS Number

1334493-07-0

Molecular Formula

C29H27F5N2O6S

Molecular Weight

626.6

Purity

>97% by HPLC

Solubility

DMSO (100 mg/ml)

Handling

Protect from air and light

Country of origin

USA

Storage temperature

+2 to +8 ◦C

Shipping Condition

Shelf life

24 months

MDL number

MFCD29477477

PubChem CID

53388144

SMILES

CN(CC(=O)N(CC1=CC=C(C=C1)C2CCCCC2)C3=CC(=C(C=C3)C(=O)O)O)S(=O)(=O)C4=C(C(=C(C(=C4F)F)F)F)F

InChI

InChI=1S/C29H27F5N2O6S/c1-35(43(41,42)28-26(33)24(31)23(30)25(32)27(28)34)15-22(38)36(19-11-12-20(29(39)40)21(37)13-19)14-16-7-9-18(10-8-16)17-5-3-2-4-6-17/h7-13,17,37H,2-6,14-15H2,1H3,(H,39,40)

InChI key

WNVSFFVDMUSXSX-UHFFFAOYSA-N

BP-1-102 is a potent and selective STAT3 inhibitor, binds Stat3 with an affinity Kd of 504 nM and blocks Stat3-phospho-tyrosine (pTyr) peptide interactions and Stat3 activation at 4-6.8 μM.