Argonaute-2 Inhibitor, BCI-137

An Argonaute-2 inhibitor

Cat. No.: AUR10089

CAS Number: 112170-24-8

Documents:

SizePrice

25 mg

$ 225

Tags Argonaute-2 inhibitor CAS#112170-24-8 112170-24-8 Auroramedbiochem

Alternate Names

2-(2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamido)propanoic acid; BCI-137

Appearance

Off-white solid

Formulation

N/A

CAS Number

112170-24-8

Molecular Formula

C11H11N3O6S

Molecular Weight

313.29

Purity

≥97% by HPLC

Solubility

DMSO (100 mg/ml)

Handling

Protect from air and light

Country of origin

USA

Storage temperature

+2°C to +8°C

Shipping Condition

Shelf life

24 months

MDL number

MFCD05148320

PubChem CID

3157172

SMILES

CC(C(=O)O)NS(=O)(=O)C1=CC2=C(C=C1)NC(=O)C(=O)N2

InChI

InChI=1S/C11H11N3O6S/c1-5(11(17)18)14-21(19,20)6-2-3-7-8(4-6)13-10(16)9(15)12-7/h2-5,14H,1H3,(H,12,15)(H,13,16)(H,17,18)

InChI key

VMSRTLYZOWBBFW-UHFFFAOYSA-N

A cell-permeable compound that directly and reversibly interacts with miRNA binding domain of Argonaute-2 (Kd = 126 µM) and inhibits binding of miR-20a, miR-26a, miR-107, miR-223 & let-7a to Ago2.

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