NMDAR2C/2D Inhibitor, DQP-1105

A noncompetitive NMDA receptor antagonist

Cat. No.: AUR10678

CAS Number: 380560-89-4

Documents:

SizePrice

50 mg

$ 725

Tags DQP-1105 DQP1105 NMDA receptor antagonist CAS#380560-89-4 380560-89-4 Auroramedbiochem

Alternate Names

4-[3-(4-bromophenyl)-5-(6-methyl-2-oxo-4-phenyl-3H-quinolin-3-yl)-3,4-dihydropyrazol-2-yl]-4-oxobutanoic acid

Appearance

Yellowish white solid

Formulation

N/A

CAS Number

380560-89-4

Molecular Formula

C29H24BrN3O4

Molecular Weight

558.43

Purity

≥97% by LCMS

Solubility

DMSO (>40 mg/ml)

Handling

Protect from air and light

Country of origin

USA

Storage temperature

-20°C

Shipping Condition

gel pack

Shelf life

24 months

MDL number

N/A

PubChem CID

252158108

SMILES

CC1=CC=C2C(C(C3=CC=CC=C3)=C(C4=NN(C(CCC(O)=O)=O)C(C5=CC=C(Br)C=C5)C4)C(N2)=O)=C1

InChI

InChI=1S/C29H24BrN3O4/c1-17-7-12-22-21(15-17)27(19-5-3-2-4-6-19)28(29(37)31-22)23-16-24(18-8-10-20(30)11-9-18)33(32-23)25(34)13-14-26(35)36/h2-12,15,24H,13-14,16H2,1H3,(H,31,37)(H,35,36)

InChI key

MVYNQMRZRULRIE-UHFFFAOYSA-N

DQP 1105 is a noncompetitive NMDA receptor antagonist; displays over 50-fold selectivity for GluN2D- and GluN2C-containing receptors over GluN2B-, GluK2-, GluA1- and GluN2A-containing receptors (IC50 values are 2.7, 8.5, 121, 153, 198 and 206 μM, respectively).

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