MPS1 Inhibitor, NMS-P715

An ATP-competitive inhibitor of MPS1

Cat. No.: AUR11378

CAS Number: 1202055-32-0

Documents:

SizePrice

50 mg

$ 1025

Tags NMS-P715 NMSP715 MPS1 inhibitor ATP-competitive 1202055-32-0 CAS#1202055-32-0 Auroramedbiochem

Alternate Names

N-(2,6-diethylphenyl)-1-methyl-8-[4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy)anilino]-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide

Appearance

White solid

Formulation

N/A

CAS Number

1202055-32-0

Molecular Formula

C35H39F3N8O3

Molecular Weight

676.73

Purity

≥96% by HPLC

Solubility

DMSO (10 mg/ml)

Handling

Protect from air and light

Country of origin

USA

Storage temperature

+2 to +8 ◦C

Shipping Condition

Shelf life

24 months

MDL number

N/A

PubChem CID

44556162

SMILES

CCC1=C(C(=CC=C1)CC)NC(=O)C2=NN(C3=C2CCC4=CN=C(N=C43)NC5=C(C=C(C=C5)C(=O)NC6CCN(CC6)C)OC(F)(F)F)C

InChI

InChI=1S/C35H39F3N8O3/c1-5-20-8-7-9-21(6-2)28(20)42-33(48)30-25-12-10-23-19-39-34(43-29(23)31(25)46(4)44-30)41-26-13-11-22(18-27(26)49-35(36,37)38)32(47)40-24-14-16-45(3)17-15-24/h7-9,11,13,18-19,24H,5-6,10,12,14-17H2,1-4H3,(H,40,47)(H,42,48)(H,39,41,43)

InChI key

JFOAJUGFHDCBJJ-UHFFFAOYSA-N

NMS-P715 is a selective, ATP-competitive inhibitor of MPS1, with an IC50 of 182 nM..