MIF Antagonist IV, RDR03785

A MIF inhibitor

Cat. No.: AUR10622

CAS Number: 289657-30-3

Documents:

SizePrice

10 mg

$ 175

Tags MIF Antagonist IV RDR03785 MIF taurtomerase activity inhibitor CAS#289657-30-3 289657-30-3 Auroramedbiochem

Alternate Names

6-[morpholin-4-yl-[4-(trifluoromethyl)phenyl]methyl]-1,3-benzodioxol-5-ol

Appearance

Cream solid

Formulation

N/A

CAS Number

289657-30-3

Molecular Formula

C19H18F3NO4

Molecular Weight

381.35

Purity

≥97% by HPLC

Solubility

DMSO (50 mg/ml)

Handling

Protect from air and light

Country of origin

USA

Storage temperature

+2 to +8 ◦C

Shipping Condition

Shelf life

24 months

MDL number

N/A

PubChem CID

2725942

SMILES

C1COCCN1C(C2=CC=C(C=C2)C(F)(F)F)C3=CC4=C(C=C3O)OCO4

InChI

InChI=1S/C19H18F3NO4/c20-19(21,22)13-3-1-12(2-4-13)18(23-5-7-25-8-6-23)14-9-16-17(10-15(14)24)27-11-26-16/h1-4,9-10,18,24H,5-8,11H2

InChI key

AWQPMEGCCWPTRI-UHFFFAOYSA-N

RDR-03785 is a cell-permeable morpholino-benzodioxol compound that inhibits MIF tautomerase activity (Ki and IC50 = 0.57 and 2.4 µM, respectively) via direct non-covalent MIF interaction (KD = 24.5 µM).

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