LTA4 Epoxide Hydrolase Inhibitor, ARM1

LTA4H inhibitor

Cat. No.: AUR10554

CAS Number: 68729-05-5

Documents:

SizePrice

10 mg

$ 125

Tags LTA4 Epoxide Hydrolase LTA4H inhibitor CAS#68729-05-5 68729-05-5 Auroramedbiochem

Alternate Names

4-(4-Benzylphenyl)-thiazol-2-amine; Leukotriene A4 Epoxide Hydrolase Inhibitor; ARM1

Appearance

Off-white solid

Formulation

N/A

CAS Number

68729-05-5

Molecular Formula

C16H14N2S

Molecular Weight

266.36

Purity

≥98% by HPLC

Solubility

DMSO (100 mg/ml)

Handling

Protect from air and light

Country of origin

USA

Storage temperature

+2 to +8 ◦C

Shipping Condition

Shelf life

24 months

MDL number

N/A

PubChem CID

3768902

SMILES

C1=CC=C(C=C1)CC2=CC=C(C=C2)C3=CSC(=N3)N

InChI

InChI=1S/C16H14N2S/c17-16-18-15(11-19-16)14-8-6-13(7-9-14)10-12-4-2-1-3-5-12/h1-9,11H,10H2,(H2,17,18)

InChI key

XYDVHKCVOMGRSY-UHFFFAOYSA-N

ARM1 acts as a selective inhibitor against the epoxide hydrolase activity of leukotriene A4 hydrolase (LTA4H; Ki = 2.3 µM) and inhibits A23187- induced leukotriene B4 (LTB4) synthesis in primary human polymorphonuclear neutrophil (PMN) cultures (IC50 = 0.5 µM).