LSD1 Inhibitor VII, SP-2509

A histone demethylase LSD1 inhibitor

Cat. No.: AUR10551

CAS Number: 1423715-09-6

Documents:

SizePrice

100 mg

$ 975

Tags SP-2509 SP2509 LSD1 inhibitor lysine demethylase Inhibitor Epigenetics CAS#1423715-09-6 1423715-09-6 Auroramedbiochem

Alternate Names

N-[(E)-1-(5-chloro-2-hydroxyphenyl)ethylideneamino]-3-morpholin-4-ylsulfonylbenzamide

Appearance

Off-white solid

Formulation

N/A

CAS Number

1423715-09-6

Molecular Formula

C19H20ClN3O5S

Molecular Weight

437.9

Purity

≥98% by HPLC

Solubility

DMSO (100 mg/ml)

Handling

Protect from air and light

Country of origin

USA

Storage temperature

+2 to +8 ◦C

Shipping Condition

Shelf life

24 months

MDL number

N/A

PubChem CID

135743577

SMILES

CC(=NNC(=O)C1=CC(=CC=C1)S(=O)(=O)N2CCOCC2)C3=C(C=CC(=C3)Cl)O

InChI

InChI=1S/C19H20ClN3O5S/c1-13(17-12-15(20)5-6-18(17)24)21-22-19(25)14-3-2-4-16(11-14)29(26,27)23-7-9-28-10-8-23/h2-6,11-12,24H,7-10H2,1H3,(H,22,25)/b21-13+

InChI key

NKUDGJUBIVEDTF-FYJGNVAPSA-N

SP-2509 is a selective histone demethylase LSD1 inhibitor with IC50 of 13 nM, showing no activity against MAO-A, MAO-B, lactate dehydrogenase and glucose oxidase. SP-2509 induces apoptosis and promotes autophagy.