JHDM Inhibitor VII, JIB-04

a selective inihibitor of Jumonji demethylases

Cat. No.: AUR10522

CAS Number: 199596-05-9

Documents:

SizePrice

50 mg

$ 475

Tags JIB-04 JIB04 Jumonji demethylases inhibitor epigenetics CAS#199596-05-9 199596-05-9 Auroramedbiochem

Alternate Names

(E)-5-chloro-2-(2-(phenyl(pyridin-2-yl)methylene)hydrazinyl)pyridine

Appearance

Light beige solid

Formulation

N/A

CAS Number

199596-05-9

Molecular Formula

C17H13ClN4

Molecular Weight

308.77

Purity

≥98% by HPLC

Solubility

DMSO (100 mg/ml)

Handling

Protect from air and light

Country of origin

USA

Storage temperature

+2 to +8 ◦C

Shipping Condition

Shelf life

24 months

MDL number

N/A

PubChem CID

6519698

SMILES

C1=CC=C(C=C1)C(=NNC2=NC=C(C=C2)Cl)C3=CC=CC=N3

InChI

InChI=1S/C17H13ClN4/c18-14-9-10-16(20-12-14)21-22-17(13-6-2-1-3-7-13)15-8-4-5-11-19-15/h1-12H,(H,20,21)/b22-17+

InChI key

YHHFKWKMXWRVTJ-OQKWZONESA-N

JIB-04 is a selective inihibitor of Jumonji demethylases without inhibiting other α-ketoglutarate-dependent hydroxylases or histone-modifying enzymes including amine oxidase LSD1 (also known as KDM1A), which demethylates histone lysines

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