IRE1 Inhibitor IV, KIRA6

An ATP-competitive allosteric IRE1α inhibitor

Cat. No.: AUR10513

CAS Number: 1589527-65-0

Documents:

SizePrice

100 mg

$ 975

Tags KIRA6 IRE1 Inhibitor IV ATP-competitive allosrteric IRE1α inhibitor CAS#1589527-65-0 1589527-65-0 Auroramedbiochem

Alternate Names

1-[4-(8-amino-3-tert-butylimidazo[1,5-a]pyrazin-1-yl)naphthalen-1-yl]-3-[3-(trifluoromethyl)phenyl]urea

Appearance

Off-white to brown solid

Formulation

N/A

CAS Number

1589527-65-0

Molecular Formula

C28H25F3N6O

Molecular Weight

518.5

Purity

≥95% by HPLC

Solubility

DMSO (50 mg/ml)

Handling

Protect from air and light

Country of origin

USA

Storage temperature

+2 to +8 ◦C

Shipping Condition

Shelf life

24 months

MDL number

N/A

PubChem CID

73425700

SMILES

CC(C)(C)C1=NC(=C2N1C=CN=C2N)C3=CC=C(C4=CC=CC=C43)NC(=O)NC5=CC=CC(=C5)C(F)(F)F

InChI

InChI=1S/C28H25F3N6O/c1-27(2,3)25-36-22(23-24(32)33-13-14-37(23)25)20-11-12-21(19-10-5-4-9-18(19)20)35-26(38)34-17-8-6-7-16(15-17)28(29,30)31/h4-15H,1-3H3,(H2,32,33)(H2,34,35,38)

InChI key

NOHQEAFAESMMDX-UHFFFAOYSA-N

KIRA6 is an ATP-competitive allosteric IRE1α inhibitor, promoting cell survival under ER stress.

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