Fasentin
A potent glucose uptake inhibitor
Cat. No.: AUR10368
CAS Number: 392721-37-8
Documents:
$ 325
Alternate Names
N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide
Appearance
Off-white solid
Formulation
N/A
CAS Number
392721-37-8
Molecular Formula
C11H9ClF3NO2
Molecular Weight
279.6
Purity
≥95% by LCMS
Solubility
DMSO (20 mg/ml)
Handling
Protect from air and light
Country of origin
USA
Storage temperature
+2 to +8 ◦C
Shipping Condition
RT
Shelf life
24 months
MDL number
MFCD01001285
PubChem CID
879520
SMILES
CC(=O)CC(=O)NC1=CC(=C(C=C1)Cl)C(F)(F)F
InChI
InChI=1S/C11H9ClF3NO2/c1-6(17)4-10(18)16-7-2-3-9(12)8(5-7)11(13,14)15/h2-3,5H,4H2,1H3,(H,16,18)
InChI key
GNYIJZMBLZXJEJ-UHFFFAOYSA-N
Fasentin, a potent glucose uptake inhibitor, inhibits GLUT-1/GLUT-4 transporters. Fasentin preferentially inhibits GLUT4 (IC50=68 μM) over GLUT1. Fasentin is a death receptor stimuli (FAS) sensitizer and sensitizes cells to FAS-induced cell death.
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