TRPV4 Antagonist I, RN-1734

A TRPV4 agonist

Cat. No.: AUR11118

CAS Number: 946387-07-1

Documents:

SizePrice

100 mg

$ 675

Tags RN-1734 RN1734 TRPV4 agonist 4α-PDD CAS#946387-07-1 946387-07-1 Auroramedbiochem

Alternate Names

2,4-dichloro-N-propan-2-yl-N-[2-(propan-2-ylamino)ethyl]benzenesulfonamide

Appearance

Yellow solid

Formulation

n/a

CAS Number

946387-07-1

Molecular Formula

C14H22Cl2N2O2S

Molecular Weight

353.3

Purity

≥99% by TLC

Solubility

DMSO (>20 mg/ml)

Handling

Protect from air and light

Country of origin

USA

Storage temperature

+2 to +8 ◦C

Shipping Condition

Shelf life

24 months

MDL number

MFCD00129453

PubChem CID

3601086

SMILES

CC(C)NCCN(C(C)C)S(=O)(=O)C1=C(C=C(C=C1)Cl)Cl

InChI

InChI=1S/C14H22Cl2N2O2S/c1-10(2)17-7-8-18(11(3)4)21(19,20)14-6-5-12(15)9-13(14)16/h5-6,9-11,17H,7-8H2,1-4H3

InChI key

IHYZMEAZAIFMTN-UHFFFAOYSA-N

RN-1734 is a cell-permeable benzenesulfonamide compound that selectively antagonizes TRPV4 agonist 4α-PDD- stimulated Ca2+ influx (IC50 = 2.3, 3.2 and 5.9 µM, respectively.

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