TLR1-TLR2 Agonist II, CU-T12-9

A potent TLR1/2 agonist

Cat. No.: AUR11095

CAS Number: 1821387-73-8

Documents:

SizePrice

10 mg

$ 175

Tags CU-T12-9 CUT12-9 TLR1/2 agonist toll like receptor agonist CAS#1821387-73-8 1821387-73-8 Auroramedbiochem

Alternate Names

N-methyl-4-nitro-2-[4-[4-(trifluoromethyl)phenyl]imidazol-1-yl]aniline; CU-T12-9

Appearance

Yellow solid

Formulation

n/a

CAS Number

1821387-73-8

Molecular Formula

C17H13F3N4O2

Molecular Weight

362.31

Purity

≥98% by HPLC

Solubility

DMSO (50 mg/ml)

Handling

Protect from air and light

Country of origin

USA

Storage temperature

+2 to +8 ◦C

Shipping Condition

Shelf life

24 months

MDL number

n/a

PubChem CID

91826088

SMILES

CNC1=C(C=C(C=C1)[N+](=O)[O-])N2C=C(N=C2)C3=CC=C(C=C3)C(F)(F)F

InChI

InChI=1S/C17H13F3N4O2/c1-21-14-7-6-13(24(25)26)8-16(14)23-9-15(22-10-23)11-2-4-12(5-3-11)17(18,19)20/h2-10,21H,1H3

InChI key

LITXVDAFEYLWQE-UHFFFAOYSA-N

CU-T12-9 is a potent TLR1/2 agonist. It acts by activating the NF-kB pathway, upregulating proinflammatory cytokines, and enhancing TLR1 and TLR2 dimerization.

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