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Tdp1 Inhibitor, CD00509

Tdp1 Inhibitor, CD00509

A specific Tdp1 inhibitor

Cat. No.: AUR11042

CAS Number: n/a

Documents:              

SizePrice

$ 175 
  
Tags CD00509 CD-00509 Tdp1 inhibitor Auroramedbiochem

Alternate Names

CD00509

Appearance

Yellow solid

Formulation

n/a

CAS Number

n/a

Molecular Formula

C9H6N2O3S

Molecular Weight

222.22

Purity

≥97% by LCMS

Solubility

DMSO

Handling

Protect from air and light

Country of origin

USA

Storage temperature

+2 to +8 ◦C

Shipping Condition

RT

Shelf life

24 months

MDL number

n/a

PubChem CID

n/a

SMILES

n/a

InChI

n/a

InChI key

n/a

CD00509 is a potent and specific inhibitor of tyrosyl-DNA phosphodiesterase 1 (Tdp1; IC50 = 710 nM) and increases the number of g-H2AX foci in MCF-7 cells. Shown to sensitize MCF-7 cells to camptothecin (CPT), increase DNA breaks, and reduce cell proliferation. 

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