KL001
A cryptochrome protein (CRY) stabilizer
Cat. No.: AUR10223
CAS Number: 309928-48-1
Documents:
$ 225
Alternate Names
N-[3-(9H-carbazol-9-yl)-2-hydroxypropyl]-N-(2-furanylmethyl)-methanesulfonamide; KL-001
Appearance
White solid
Formulation
N/A
CAS Number
309928-48-1
Molecular Formula
C21H22N2O4S
Molecular Weight
398.5
Purity
≥98% by HPLC
Solubility
DMSO (>35 mg/ml)
Handling
Protect from air and light
Country of origin
USA
Storage temperature
+2 to +8 ◦C
Shipping Condition
RT
Shelf life
24 months
MDL number
PubChem CID
2888648
SMILES
CS(=O)(=O)N(CC1=CC=CO1)CC(CN2C3=CC=CC=C3C4=CC=CC=C42)O
InChI
InChI=1S/C21H22N2O4S/c1-28(25,26)22(15-17-7-6-12-27-17)13-16(24)14-23-20-10-4-2-8-18(20)19-9-3-5-11-21(19)23/h2-12,16,24H,13-15H2,1H3
InChI key
OQAFDLPAPSSOHY-UHFFFAOYSA-N
KL001 is a cryptochrome protein (CRY) stabilizer; blocks proteasome-mediated degradation of CRY1 and CRY2. Lengthens circadian period in mouse NIH-3T3 fibroblasts without altering casein kinase activity.
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